Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM78434.1KEGG: tbo:Thebr_1467 hypothetical protein. (70 aa)    
Predicted Functional Partners:
obg
GTP1/OBG sub domain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
  
  
 0.941
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
    0.660
AEM78432.1
PFAM: Protein of unknown function DUF464; KEGG: tbo:Thebr_1469 hypothetical protein.
  
    0.659
rpmA
TIGRFAM: Ribosomal protein L27; HAMAP: Ribosomal protein L27; KEGG: tbo:Thebr_1468 50S ribosomal protein L27; PFAM: Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
  
    0.659
AEM78288.1
NusG antitermination factor; Participates in transcription elongation, termination and antitermination.
   
    0.493
nusG
NusG antitermination factor; Participates in transcription elongation, termination and antitermination.
   
    0.493
rpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
    0.491
rplA
Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
   
    0.482
AEM78437.1
Metal dependent phosphohydrolase; TIGRFAM: Conserved hypothetical protein CHP00488; HDIG; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; KEGG: tit:Thit_0857 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD region.
  
    0.462
tdk
KEGG: tbo:Thebr_2159 thymidine kinase; HAMAP: Thymidine kinase, subgroup; PFAM: Thymidine kinase.
   
    0.460
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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