| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEM77537.1 | AEM78456.1 | Thewi_0021 | Thewi_1028 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | PFAM: Haloacid dehalogenase-like hydrolase; KEGG: thx:Thet_0841 haloacid dehalogenase domain-containing protein hydrolase. | 0.604 |
| AEM77537.1 | AEM78458.1 | Thewi_0021 | Thewi_1030 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | KEGG: tbo:Thebr_1441 DNA internalization-like competence protein ComEC/Rec2; TIGRFAM: Competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein. | 0.428 |
| AEM77537.1 | guaB | Thewi_0021 | Thewi_0666 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.783 |
| AEM77537.1 | nadE | Thewi_0021 | Thewi_0754 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.751 |
| AEM77537.1 | ribBA | Thewi_0021 | Thewi_0023 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
| AEM78455.1 | AEM78456.1 | Thewi_1027 | Thewi_1028 | PFAM: Transposase, IS4-like; KEGG: tbo:Thebr_1887 transposase IS4 family protein. | PFAM: Haloacid dehalogenase-like hydrolase; KEGG: thx:Thet_0841 haloacid dehalogenase domain-containing protein hydrolase. | 0.499 |
| AEM78455.1 | AEM78457.1 | Thewi_1027 | Thewi_1029 | PFAM: Transposase, IS4-like; KEGG: tbo:Thebr_1887 transposase IS4 family protein. | KEGG: tbo:Thebr_1442 beta-lactamase domain-containing protein. | 0.499 |
| AEM78455.1 | AEM78458.1 | Thewi_1027 | Thewi_1030 | PFAM: Transposase, IS4-like; KEGG: tbo:Thebr_1887 transposase IS4 family protein. | KEGG: tbo:Thebr_1441 DNA internalization-like competence protein ComEC/Rec2; TIGRFAM: Competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein. | 0.499 |
| AEM78455.1 | AEM78459.1 | Thewi_1027 | Thewi_1031 | PFAM: Transposase, IS4-like; KEGG: tbo:Thebr_1887 transposase IS4 family protein. | KEGG: thx:Thet_0844 DNA polymerase III subunit delta; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta. | 0.499 |
| AEM78456.1 | AEM77537.1 | Thewi_1028 | Thewi_0021 | PFAM: Haloacid dehalogenase-like hydrolase; KEGG: thx:Thet_0841 haloacid dehalogenase domain-containing protein hydrolase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.604 |
| AEM78456.1 | AEM78455.1 | Thewi_1028 | Thewi_1027 | PFAM: Haloacid dehalogenase-like hydrolase; KEGG: thx:Thet_0841 haloacid dehalogenase domain-containing protein hydrolase. | PFAM: Transposase, IS4-like; KEGG: tbo:Thebr_1887 transposase IS4 family protein. | 0.499 |
| AEM78456.1 | AEM78457.1 | Thewi_1028 | Thewi_1029 | PFAM: Haloacid dehalogenase-like hydrolase; KEGG: thx:Thet_0841 haloacid dehalogenase domain-containing protein hydrolase. | KEGG: tbo:Thebr_1442 beta-lactamase domain-containing protein. | 0.793 |
| AEM78456.1 | AEM78458.1 | Thewi_1028 | Thewi_1030 | PFAM: Haloacid dehalogenase-like hydrolase; KEGG: thx:Thet_0841 haloacid dehalogenase domain-containing protein hydrolase. | KEGG: tbo:Thebr_1441 DNA internalization-like competence protein ComEC/Rec2; TIGRFAM: Competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein. | 0.848 |
| AEM78456.1 | AEM78459.1 | Thewi_1028 | Thewi_1031 | PFAM: Haloacid dehalogenase-like hydrolase; KEGG: thx:Thet_0841 haloacid dehalogenase domain-containing protein hydrolase. | KEGG: thx:Thet_0844 DNA polymerase III subunit delta; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta. | 0.789 |
| AEM78456.1 | AEM78987.1 | Thewi_1028 | Thewi_1584 | PFAM: Haloacid dehalogenase-like hydrolase; KEGG: thx:Thet_0841 haloacid dehalogenase domain-containing protein hydrolase. | PFAM: Protein of unknown function DUF1614; KEGG: tbo:Thebr_0854 hypothetical protein. | 0.466 |
| AEM78456.1 | AEM79378.1 | Thewi_1028 | Thewi_2010 | PFAM: Haloacid dehalogenase-like hydrolase; KEGG: thx:Thet_0841 haloacid dehalogenase domain-containing protein hydrolase. | KEGG: tbo:Thebr_0550 MIP family channel protein; TIGRFAM: Aquaporin; PFAM: Major intrinsic protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.556 |
| AEM78456.1 | guaB | Thewi_1028 | Thewi_0666 | PFAM: Haloacid dehalogenase-like hydrolase; KEGG: thx:Thet_0841 haloacid dehalogenase domain-containing protein hydrolase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.485 |
| AEM78456.1 | nadE | Thewi_1028 | Thewi_0754 | PFAM: Haloacid dehalogenase-like hydrolase; KEGG: thx:Thet_0841 haloacid dehalogenase domain-containing protein hydrolase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.433 |
| AEM78456.1 | ribBA | Thewi_1028 | Thewi_0023 | PFAM: Haloacid dehalogenase-like hydrolase; KEGG: thx:Thet_0841 haloacid dehalogenase domain-containing protein hydrolase. | GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.477 |
| AEM78457.1 | AEM78455.1 | Thewi_1029 | Thewi_1027 | KEGG: tbo:Thebr_1442 beta-lactamase domain-containing protein. | PFAM: Transposase, IS4-like; KEGG: tbo:Thebr_1887 transposase IS4 family protein. | 0.499 |
