Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM78493.1Phosphotransferase ydiA; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (270 aa)    
Predicted Functional Partners:
AEM78492.1
KEGG: tbo:Thebr_1388 CBS domain-containing protein.
 
  
 0.957
AEM78494.1
KEGG: tbo:Thebr_1386 pyruvate, phosphate dikinase; TIGRFAM: Pyruvate, phosphate dikinase; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; PEP-utilising enzyme; Belongs to the PEP-utilizing enzyme family.
 
  
 0.945
glyQS
glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.540
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
  
    0.515
AEM78495.1
TIGRFAM: HDIG; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; KEGG: tbo:Thebr_1385 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD region.
       0.497
AEM79079.1
KEGG: tbo:Thebr_0763 hypothetical protein; TIGRFAM: NGG1p interacting factor 3, NIF3; PFAM: NGG1p interacting factor 3, NIF3; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
 
     0.487
recO
DNA repair protein recO; Involved in DNA repair and RecF pathway recombination.
       0.467
AEM77678.1
PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; KEGG: tbo:Thebr_2144 pyruvate phosphate dikinase PEP/pyruvate-binding protein.
  
  
 0.460
era
GTP-binding protein Era-like-protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
    0.424
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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