Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM78533.1KEGG: thx:Thet_1477 phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2; PFAM: DAHP synthetase I/KDSA. (338 aa)    
Predicted Functional Partners:
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 
 0.988
pheA
PFAM: Prephenate dehydratase; Amino acid-binding ACT; KEGG: tbo:Thebr_1009 prephenate dehydratase.
 
  
 0.977
AEM78534.1
PFAM: Prephenate dehydrogenase; KEGG: tbo:Thebr_1011 prephenate dehydrogenase.
 
  
 0.918
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
  
 0.905
AEM78932.1
KEGG: tbo:Thebr_0920 phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2; PFAM: DAHP synthetase I/KDSA.
  
  
 
0.902
AEM77804.1
Transketolase domain-containing protein; PFAM: Transketolase, N-terminal; KEGG: tbo:Thebr_0504 transketolase domain-containing protein.
    
  0.806
AEM77805.1
Transketolase central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; KEGG: thx:Thet_1947 transketolase central region.
    
  0.806
AEM79132.1
Transketolase central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; KEGG: thx:Thet_1012 transketolase domain-containing protein.
    
  0.806
AEM79133.1
Transketolase domain-containing protein; PFAM: Transketolase, N-terminal; KEGG: thx:Thet_1011 transketolase.
    
  0.806
AEM79426.1
Transketolase central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; KEGG: thx:Thet_1947 transketolase central region.
    
  0.806
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.