Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM78623.1Ferric uptake regulator, Fur family; PFAM: Ferric-uptake regulator; KEGG: tbo:Thebr_1083 ferric-uptake regulator; Belongs to the Fur family. (146 aa)    
Predicted Functional Partners:
rnj
Ribocuclease J; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
       0.584
AEM78622.1
PFAM: Protein of unknown function DUF1292; KEGG: thx:Thet_1411 hypothetical protein.
  
    0.571
AEM78625.1
PFAM: Protein of unknown function DUF964; KEGG: tbo:Thebr_1085 hypothetical protein; Belongs to the UPF0342 family.
       0.564
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.548
AEM78626.1
PFAM: Protein of unknown function DUF988; KEGG: thx:Thet_1407 hypothetical protein.
  
    0.493
AEM78620.1
PFAM: Protein of unknown function DUF965, bacterial; KEGG: tit:Thit_1042 protein of unknown function DUF965; Belongs to the UPF0297 family.
  
    0.489
AEM78621.1
Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
       0.487
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
       0.482
AEM78628.1
PFAM: O-methyltransferase, family 3; KEGG: tbo:Thebr_1088 O-methyltransferase family 3.
       0.478
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
    0.422
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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