close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM78629.1PFAM: Peptidase U32; KEGG: tbo:Thebr_1089 peptidase U32. (405 aa)    
Predicted Functional Partners:
AEM78628.1
PFAM: O-methyltransferase, family 3; KEGG: tbo:Thebr_1088 O-methyltransferase family 3.
 
  
 0.917
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
  
    0.833
AEM78630.1
PFAM: Penicillin-binding protein, transpeptidase; KEGG: tbo:Thebr_1090 penicillin-binding protein transpeptidase.
       0.646
AEM78625.1
PFAM: Protein of unknown function DUF964; KEGG: tbo:Thebr_1085 hypothetical protein; Belongs to the UPF0342 family.
       0.585
rnj
Ribocuclease J; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
       0.557
AEM78626.1
PFAM: Protein of unknown function DUF988; KEGG: thx:Thet_1407 hypothetical protein.
       0.549
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
    0.533
AEM78631.1
RNA polymerase, sigma 28 subunit, SigK; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.522
AEM78604.1
PFAM: UBA/THIF-type NAD/FAD binding fold; KEGG: tpd:Teth39_1037 UBA/ThiF-type NAD/FAD binding protein.
 
     0.439
AEM79105.1
PFAM: Phosphoribulokinase/uridine kinase; KEGG: tbo:Thebr_0737 AAA ATPase.
  
    0.435
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.