STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM78632.1KEGG: tbo:Thebr_1092 HAD superfamily (subfamily IIIA) phosphatase; TIGRFAM: HAD-superfamily phosphatase, subfamily IIIA; HAD-superfamily hydrolase, subfamily IIIA; PFAM: Haloacid dehalogenase-like hydrolase. (166 aa)    
Predicted Functional Partners:
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
    0.898
AEM78631.1
RNA polymerase, sigma 28 subunit, SigK; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.684
AEM78634.1
KEGG: tbo:Thebr_1094 type II secretion system protein E; PFAM: Type II secretion system protein E; General secretory system II, protein E, N-terminal; SMART: ATPase, AAA+ type, core.
       0.650
AEM78635.1
Twitching motility protein; TIGRFAM: Pilus retraction protein PilT; PFAM: Type II secretion system protein E; KEGG: tbo:Thebr_1095 twitching motility protein; SMART: ATPase, AAA+ type, core.
       0.626
AEM78636.1
KEGG: tmt:Tmath_1113 type II secretion system F domain protein; manually curated; PFAM: Type II secretion system F domain.
       0.624
AEM78652.1
PFAM: Peptidase M24, structural domain; Creatinase; KEGG: tbo:Thebr_1112 peptidase M24; Belongs to the peptidase M24B family.
 
     0.561
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
     0.548
AEM78637.1
KEGG: ttm:Tthe_1280 Tfp pilus assembly protein PilE-like protein protein.
       0.536
AEM78643.1
PFAM: Late competence development protein ComFB; KEGG: tmt:Tmath_1120 late competence development protein ComFB.
 
     0.534
AEM78437.1
Metal dependent phosphohydrolase; TIGRFAM: Conserved hypothetical protein CHP00488; HDIG; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; KEGG: tit:Thit_0857 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD region.
 
  
 0.533
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.