STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM78669.1KEGG: tbo:Thebr_1129 hypothetical protein. (184 aa)    
Predicted Functional Partners:
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
 
    0.900
AEM78671.1
TIGRFAM: Haemolysin A; PFAM: RNA-binding S4; Ribosomal RNA methyltransferase RrmJ/FtsJ; KEGG: tbo:Thebr_1131 hemolysin A; SMART: RNA-binding S4.
     
 0.880
argR
Arginine repressor, ArgR; Regulates arginine biosynthesis genes.
 
  
 0.771
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.742
AEM79609.1
PFAM: Ribosomal protein L7Ae/L30e/S12e/Gadd45; KEGG: tbo:Thebr_0378 50S ribosomal protein L7Ae/L30e/S12e/Gadd45.
  
     0.739
AEM78674.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
     
 0.682
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.602
AEM79581.1
KEGG: tbo:Thebr_0406 hypothetical protein.
  
     0.564
AEM78675.1
KEGG: tbo:Thebr_1135 stage IV sporulation protein B; TIGRFAM: Peptidase S55, sporulation stage IV, protein B; PFAM: Peptidase S55, SpoIVB.
       0.506
AEM78676.1
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
       0.447
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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