STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM78676.1Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (260 aa)    
Predicted Functional Partners:
AEM78675.1
KEGG: tbo:Thebr_1135 stage IV sporulation protein B; TIGRFAM: Peptidase S55, sporulation stage IV, protein B; PFAM: Peptidase S55, SpoIVB.
   
 0.976
AEM77656.1
KEGG: tbo:Thebr_2163 response regulator receiver; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region.
     
  0.900
AEM78998.1
RNA polymerase, sigma 28 subunit, SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.889
AEM77684.1
TIGRFAM: Sporulation stage III, transcriptional regulator SpoIIID; KEGG: tbo:Thebr_2141 sporulation transcriptional regulator SpoIIID.
  
   
 0.860
AEM78977.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.858
AEM79686.1
TIGRFAM: Sporulation stage II, protein E; PFAM: Sporulation stage II, protein E C-terminal; KEGG: thx:Thet_2127 protein serine/threonine phosphatase; SMART: Protein phosphatase 2C-related.
  
  
 0.851
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
  
 0.844
AEM78999.1
RNA polymerase, sigma 28 subunit, SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.843
AEM78693.1
Manually curated; TIGRFAM: Stage V sporulation AD; KEGG: tbo:Thebr_1153 stage V sporulation protein AD; PFAM: Stage V sporulation AD.
  
   
 0.842
AEM79894.1
Stage V sporulation protein T; KEGG: tmt:Tmath_2137 transcriptional regulator, AbrB family; TIGRFAM: Sporulation stage V, protein T; Transcription regulator AbrB; PFAM: Transcription regulator AbrB/SpoV, predicted.
  
   
 0.841
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.