STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM78688.1KEGG: tbo:Thebr_1148 anti-sigma F factor antagonist; TIGRFAM: Anti-sigma F factor antagonist; Anti-sigma factor antagonist; PFAM: Sulphate transporter/antisigma-factor antagonist STAS. (111 aa)    
Predicted Functional Partners:
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.997
AEM78690.1
KEGG: thx:Thet_1343 RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; TIGRFAM: RNA polymerase sigma-F type; RNA polymerase sigma-70; RNA polymerase sigma-B/F/G type; PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 3; RNA polymerase sigma-70 region 4; Belongs to the sigma-70 factor family.
 
  
 0.965
AEM78693.1
Manually curated; TIGRFAM: Stage V sporulation AD; KEGG: tbo:Thebr_1153 stage V sporulation protein AD; PFAM: Stage V sporulation AD.
 
   
 0.841
AEM78692.1
KEGG: tbo:Thebr_1152 stage V sporulation protein AC; TIGRFAM: Sporulation stage V, protein AC; PFAM: SpoVA.
 
   
 0.839
AEM78694.1
KEGG: tbo:Thebr_1154 stage V sporulation protein AE; TIGRFAM: Sporulation stage V, protein AE; PFAM: SpoVA.
 
     0.807
AEM79686.1
TIGRFAM: Sporulation stage II, protein E; PFAM: Sporulation stage II, protein E C-terminal; KEGG: thx:Thet_2127 protein serine/threonine phosphatase; SMART: Protein phosphatase 2C-related.
  
  
 0.804
AEM79883.1
KEGG: thx:Thet_2320 stage II sporulation protein R; TIGRFAM: Sporulation stage II, protein R; PFAM: Sporulation stage II, protein R.
  
   
 0.799
AEM79000.1
Hypothetical protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
  
 0.781
AEM78977.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.771
AEM79733.1
KEGG: tte:TTE1049 anti-sigma regulatory factor (Ser/Thr protein kinase); PFAM: ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like.
 
 
 0.760
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.