STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM78690.1KEGG: thx:Thet_1343 RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; TIGRFAM: RNA polymerase sigma-F type; RNA polymerase sigma-70; RNA polymerase sigma-B/F/G type; PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 3; RNA polymerase sigma-70 region 4; Belongs to the sigma-70 factor family. (246 aa)    
Predicted Functional Partners:
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.991
AEM78688.1
KEGG: tbo:Thebr_1148 anti-sigma F factor antagonist; TIGRFAM: Anti-sigma F factor antagonist; Anti-sigma factor antagonist; PFAM: Sulphate transporter/antisigma-factor antagonist STAS.
 
  
 0.965
AEM78692.1
KEGG: tbo:Thebr_1152 stage V sporulation protein AC; TIGRFAM: Sporulation stage V, protein AC; PFAM: SpoVA.
 
     0.877
AEM78693.1
Manually curated; TIGRFAM: Stage V sporulation AD; KEGG: tbo:Thebr_1153 stage V sporulation protein AD; PFAM: Stage V sporulation AD.
 
     0.874
AEM78694.1
KEGG: tbo:Thebr_1154 stage V sporulation protein AE; TIGRFAM: Sporulation stage V, protein AE; PFAM: SpoVA.
 
     0.871
AEM78676.1
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.766
AEM78977.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
     0.737
AEM78687.1
PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; KEGG: tbo:Thebr_1147 serine-type D-Ala-D-Ala carboxypeptidase.
 
     0.716
AEM79894.1
Stage V sporulation protein T; KEGG: tmt:Tmath_2137 transcriptional regulator, AbrB family; TIGRFAM: Sporulation stage V, protein T; Transcription regulator AbrB; PFAM: Transcription regulator AbrB/SpoV, predicted.
  
     0.714
AEM77684.1
TIGRFAM: Sporulation stage III, transcriptional regulator SpoIIID; KEGG: tbo:Thebr_2141 sporulation transcriptional regulator SpoIIID.
  
   
 0.712
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.