Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM78694.1KEGG: tbo:Thebr_1154 stage V sporulation protein AE; TIGRFAM: Sporulation stage V, protein AE; PFAM: SpoVA. (118 aa)    
Predicted Functional Partners:
AEM78693.1
Manually curated; TIGRFAM: Stage V sporulation AD; KEGG: tbo:Thebr_1153 stage V sporulation protein AD; PFAM: Stage V sporulation AD.
 
  
 0.982
AEM78692.1
KEGG: tbo:Thebr_1152 stage V sporulation protein AC; TIGRFAM: Sporulation stage V, protein AC; PFAM: SpoVA.
 
  
 0.978
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
     0.898
AEM78690.1
KEGG: thx:Thet_1343 RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; TIGRFAM: RNA polymerase sigma-F type; RNA polymerase sigma-70; RNA polymerase sigma-B/F/G type; PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 3; RNA polymerase sigma-70 region 4; Belongs to the sigma-70 factor family.
 
     0.870
AEM78688.1
KEGG: tbo:Thebr_1148 anti-sigma F factor antagonist; TIGRFAM: Anti-sigma F factor antagonist; Anti-sigma factor antagonist; PFAM: Sulphate transporter/antisigma-factor antagonist STAS.
 
     0.807
AEM78675.1
KEGG: tbo:Thebr_1135 stage IV sporulation protein B; TIGRFAM: Peptidase S55, sporulation stage IV, protein B; PFAM: Peptidase S55, SpoIVB.
  
   
 0.797
gpr
Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
  
 0.788
AEM78977.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.785
AEM79894.1
Stage V sporulation protein T; KEGG: tmt:Tmath_2137 transcriptional regulator, AbrB family; TIGRFAM: Sporulation stage V, protein T; Transcription regulator AbrB; PFAM: Transcription regulator AbrB/SpoV, predicted.
  
    0.782
AEM77684.1
TIGRFAM: Sporulation stage III, transcriptional regulator SpoIIID; KEGG: tbo:Thebr_2141 sporulation transcriptional regulator SpoIIID.
  
   
 0.779
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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