Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AEM78696.1PFAM: Peptidase M50; KEGG: tbo:Thebr_1156 peptidase M50. (202 aa)    
Predicted Functional Partners:
scpA
Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
       0.841
scpB
Chromosome segregation and condensation protein, ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
       0.841
AEM78695.1
PFAM: Polynucleotide adenylyltransferase region; KEGG: thx:Thet_1338 polynucleotide adenylyltransferase region; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
       0.792
AEM78694.1
KEGG: tbo:Thebr_1154 stage V sporulation protein AE; TIGRFAM: Sporulation stage V, protein AE; PFAM: SpoVA.
       0.570
AEM78693.1
Manually curated; TIGRFAM: Stage V sporulation AD; KEGG: tbo:Thebr_1153 stage V sporulation protein AD; PFAM: Stage V sporulation AD.
       0.561
AEM78692.1
KEGG: tbo:Thebr_1152 stage V sporulation protein AC; TIGRFAM: Sporulation stage V, protein AC; PFAM: SpoVA.
       0.557
AEM78691.1
Protein of unknown function DUF1458; PFAM: Dodecin flavoprotein; KEGG: thx:Thet_1342 hypothetical protein.
       0.453
AEM78687.1
PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; KEGG: tbo:Thebr_1147 serine-type D-Ala-D-Ala carboxypeptidase.
  
    0.416
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
     
 0.405
AEM78688.1
KEGG: tbo:Thebr_1148 anti-sigma F factor antagonist; TIGRFAM: Anti-sigma F factor antagonist; Anti-sigma factor antagonist; PFAM: Sulphate transporter/antisigma-factor antagonist STAS.
     
 0.403
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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