Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM78712.1Agmatinase; KEGG: tbo:Thebr_1172 agmatinase; TIGRFAM: Putative agmatinase; PFAM: Ureohydrolase; Belongs to the arginase family. (288 aa)    
Predicted Functional Partners:
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
 
 
 0.994
AEM78556.1
PFAM: Orn/Lys/Arg decarboxylase, major region; Orn/Lys/Arg decarboxylase, C-terminal; KEGG: tbo:Thebr_1022 Orn/Lys/Arg decarboxylase major region.
 
 
 0.945
AEM79652.1
PFAM: Aminotransferase class-III; KEGG: tbo:Thebr_0337 acetylornithine transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.944
AEM77969.1
KEGG: thx:Thet_0437 glutamate formiminotransferase; TIGRFAM: Formiminotransferase; PFAM: Formiminotransferase, N-terminal; Formiminotransferase, C-terminal.
  
    0.919
AEM77661.1
PFAM: Protein of unknown function DUF1385; KEGG: tbo:Thebr_2158 hypothetical protein.
   
    0.783
hutH
TIGRFAM: Histidine ammonia-lyase; HAMAP: Histidine ammonia-lyase; KEGG: tbo:Thebr_1523 histidine ammonia-lyase; PFAM: Phenylalanine/histidine ammonia-lyase.
  
  
 0.756
lon
Anti-sigma H sporulation factor, LonB; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
    
  0.726
leuS
KEGG: tit:Thit_0284 leucyl-tRNA synthetase; TIGRFAM: Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
   0.697
AEM78709.1
TIGRFAM: Pseudouridine synthase, RsuA and RluB/E/F; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; KEGG: tbo:Thebr_1169 pseudouridine synthase; SMART: RNA-binding S4.
       0.695
AEM78710.1
KEGG: tbo:Thebr_1170 hypothetical protein.
  
    0.656
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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