| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEM78668.1 | cmk | Thewi_1245 | Thewi_1305 | PFAM: Polyprenyl synthetase; KEGG: tbo:Thebr_1128 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | TIGRFAM: Cytidylate kinase; HAMAP: Cytidylate kinase; KEGG: tbo:Thebr_1196 cytidylate kinase; PFAM: Cytidylate kinase region; Shikimate kinase. | 0.603 |
| AEM78668.1 | dxr | Thewi_1245 | Thewi_1358 | PFAM: Polyprenyl synthetase; KEGG: tbo:Thebr_1128 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.471 |
| AEM78668.1 | dxs | Thewi_1245 | Thewi_1247 | PFAM: Polyprenyl synthetase; KEGG: tbo:Thebr_1128 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.593 |
| AEM78668.1 | ispD | Thewi_1245 | Thewi_2283 | PFAM: Polyprenyl synthetase; KEGG: tbo:Thebr_1128 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.486 |
| AEM78668.1 | ispE | Thewi_1245 | Thewi_2565 | PFAM: Polyprenyl synthetase; KEGG: tbo:Thebr_1128 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.521 |
| AEM78668.1 | ispG | Thewi_1245 | Thewi_1356 | PFAM: Polyprenyl synthetase; KEGG: tbo:Thebr_1128 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.414 |
| AEM78668.1 | ispH | Thewi_1245 | Thewi_1307 | PFAM: Polyprenyl synthetase; KEGG: tbo:Thebr_1128 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.932 |
| AEM78727.1 | AEM78731.1 | Thewi_1304 | Thewi_1308 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | PFAM: Ribosomal protein S1, RNA binding domain; KEGG: tbo:Thebr_1199 RNA-binding S1 domain-containing protein. | 0.766 |
| AEM78727.1 | cmk | Thewi_1304 | Thewi_1305 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | TIGRFAM: Cytidylate kinase; HAMAP: Cytidylate kinase; KEGG: tbo:Thebr_1196 cytidylate kinase; PFAM: Cytidylate kinase region; Shikimate kinase. | 0.936 |
| AEM78727.1 | ispH | Thewi_1304 | Thewi_1307 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.790 |
| AEM78731.1 | AEM78727.1 | Thewi_1308 | Thewi_1304 | PFAM: Ribosomal protein S1, RNA binding domain; KEGG: tbo:Thebr_1199 RNA-binding S1 domain-containing protein. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | 0.766 |
| AEM78731.1 | cmk | Thewi_1308 | Thewi_1305 | PFAM: Ribosomal protein S1, RNA binding domain; KEGG: tbo:Thebr_1199 RNA-binding S1 domain-containing protein. | TIGRFAM: Cytidylate kinase; HAMAP: Cytidylate kinase; KEGG: tbo:Thebr_1196 cytidylate kinase; PFAM: Cytidylate kinase region; Shikimate kinase. | 0.983 |
| AEM78731.1 | ispH | Thewi_1308 | Thewi_1307 | PFAM: Ribosomal protein S1, RNA binding domain; KEGG: tbo:Thebr_1199 RNA-binding S1 domain-containing protein. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.981 |
| cmk | AEM78668.1 | Thewi_1305 | Thewi_1245 | TIGRFAM: Cytidylate kinase; HAMAP: Cytidylate kinase; KEGG: tbo:Thebr_1196 cytidylate kinase; PFAM: Cytidylate kinase region; Shikimate kinase. | PFAM: Polyprenyl synthetase; KEGG: tbo:Thebr_1128 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.603 |
| cmk | AEM78727.1 | Thewi_1305 | Thewi_1304 | TIGRFAM: Cytidylate kinase; HAMAP: Cytidylate kinase; KEGG: tbo:Thebr_1196 cytidylate kinase; PFAM: Cytidylate kinase region; Shikimate kinase. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | 0.936 |
| cmk | AEM78731.1 | Thewi_1305 | Thewi_1308 | TIGRFAM: Cytidylate kinase; HAMAP: Cytidylate kinase; KEGG: tbo:Thebr_1196 cytidylate kinase; PFAM: Cytidylate kinase region; Shikimate kinase. | PFAM: Ribosomal protein S1, RNA binding domain; KEGG: tbo:Thebr_1199 RNA-binding S1 domain-containing protein. | 0.983 |
| cmk | ispH | Thewi_1305 | Thewi_1307 | TIGRFAM: Cytidylate kinase; HAMAP: Cytidylate kinase; KEGG: tbo:Thebr_1196 cytidylate kinase; PFAM: Cytidylate kinase region; Shikimate kinase. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.971 |
| dxr | AEM78668.1 | Thewi_1358 | Thewi_1245 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | PFAM: Polyprenyl synthetase; KEGG: tbo:Thebr_1128 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.471 |
| dxr | dxs | Thewi_1358 | Thewi_1247 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.986 |
| dxr | ispD | Thewi_1358 | Thewi_2283 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.986 |
