| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEM77765.1 | AEM78674.1 | Thewi_0264 | Thewi_1251 | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_2057 SMC domain-containing protein. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.491 |
| AEM77765.1 | polA | Thewi_0264 | Thewi_0961 | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_2057 SMC domain-containing protein. | 5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.970 |
| AEM77765.1 | recA | Thewi_0264 | Thewi_1331 | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_2057 SMC domain-containing protein. | Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.673 |
| AEM77765.1 | recA-2 | Thewi_0264 | Thewi_1956 | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_2057 SMC domain-containing protein. | Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.673 |
| AEM77765.1 | recX | Thewi_0264 | Thewi_1330 | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_2057 SMC domain-containing protein. | Regulatory protein recX; Modulates RecA activity; Belongs to the RecX family. | 0.527 |
| AEM77765.1 | ruvC | Thewi_0264 | Thewi_1154 | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_2057 SMC domain-containing protein. | Crossover junction endodeoxyribonuclease ruvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.401 |
| AEM77765.1 | topA | Thewi_0264 | Thewi_1404 | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_2057 SMC domain-containing protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.763 |
| AEM78674.1 | AEM77765.1 | Thewi_1251 | Thewi_0264 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Hypothetical protein; Manually curated; KEGG: tbo:Thebr_2057 SMC domain-containing protein. | 0.491 |
| AEM78674.1 | cinA | Thewi_1251 | Thewi_1332 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | KEGG: tbo:Thebr_1221 competence/damage-inducible protein CinA; TIGRFAM: Competence-induced protein CinA; CinA, C-terminal; PFAM: CinA, C-terminal; Molybdopterin binding; Belongs to the CinA family. | 0.640 |
| AEM78674.1 | polA | Thewi_1251 | Thewi_0961 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.714 |
| AEM78674.1 | radA | Thewi_1251 | Thewi_2286 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.498 |
| AEM78674.1 | recA | Thewi_1251 | Thewi_1331 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.683 |
| AEM78674.1 | recA-2 | Thewi_1251 | Thewi_1956 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.683 |
| AEM78674.1 | recX | Thewi_1251 | Thewi_1330 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Regulatory protein recX; Modulates RecA activity; Belongs to the RecX family. | 0.586 |
| AEM78674.1 | topA | Thewi_1251 | Thewi_1404 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.686 |
| cinA | AEM78674.1 | Thewi_1332 | Thewi_1251 | KEGG: tbo:Thebr_1221 competence/damage-inducible protein CinA; TIGRFAM: Competence-induced protein CinA; CinA, C-terminal; PFAM: CinA, C-terminal; Molybdopterin binding; Belongs to the CinA family. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.640 |
| cinA | polA | Thewi_1332 | Thewi_0961 | KEGG: tbo:Thebr_1221 competence/damage-inducible protein CinA; TIGRFAM: Competence-induced protein CinA; CinA, C-terminal; PFAM: CinA, C-terminal; Molybdopterin binding; Belongs to the CinA family. | 5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.634 |
| cinA | radA | Thewi_1332 | Thewi_2286 | KEGG: tbo:Thebr_1221 competence/damage-inducible protein CinA; TIGRFAM: Competence-induced protein CinA; CinA, C-terminal; PFAM: CinA, C-terminal; Molybdopterin binding; Belongs to the CinA family. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.401 |
| cinA | recA | Thewi_1332 | Thewi_1331 | KEGG: tbo:Thebr_1221 competence/damage-inducible protein CinA; TIGRFAM: Competence-induced protein CinA; CinA, C-terminal; PFAM: CinA, C-terminal; Molybdopterin binding; Belongs to the CinA family. | Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.853 |
| cinA | recA-2 | Thewi_1332 | Thewi_1956 | KEGG: tbo:Thebr_1221 competence/damage-inducible protein CinA; TIGRFAM: Competence-induced protein CinA; CinA, C-terminal; PFAM: CinA, C-terminal; Molybdopterin binding; Belongs to the CinA family. | Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.661 |