STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM78827.1KEGG: tbo:Thebr_1294 DNA protecting protein DprA; TIGRFAM: DNA recombination-mediator protein A; PFAM: DNA recombination-mediator protein A. (362 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.880
AEM78018.1
PFAM: Phosphoribosyltransferase; KEGG: tbo:Thebr_1833 phosphoribosyltransferase.
 
 
 0.860
AEM78458.1
KEGG: tbo:Thebr_1441 DNA internalization-like competence protein ComEC/Rec2; TIGRFAM: Competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein.
 
  
 0.856
AEM78832.1
Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein; PFAM: Magnesium chelatase, ChlI subunit; KEGG: thx:Thet_1194 Mg chelatase subunit ChlI; SMART: ATPase, AAA+ type, core.
 
 0.842
AEM78829.1
UPF0102 protein yraN; TIGRFAM: Uncharacterised protein family UPF0102; HAMAP: Uncharacterised protein family UPF0102; KEGG: tbo:Thebr_1296 hypothetical protein; PFAM: Uncharacterised protein family UPF0102; Belongs to the UPF0102 family.
 
    0.841
AEM79728.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; KEGG: bmd:BMD_0935 response regulator diguanylate cyclase/phosphodiesterase; SMART: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region.
  
  
 0.747
AEM78638.1
Peptidase A24A domain protein; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.722
rnhB
Ribonuclease HII/HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
 
    0.719
AEM78806.1
CheC, inhibitor of MCP methylation / FliN fusion protein; KEGG: tbo:Thebr_1273 flagellar motor switch protein FliN; TIGRFAM: Flagellar motor switch FliN; PFAM: Surface presentation of antigen (SpoA); CheC-like protein.
  
    0.674
hslV
ATP-dependent protease hslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
   0.658
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.