STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM78829.1UPF0102 protein yraN; TIGRFAM: Uncharacterised protein family UPF0102; HAMAP: Uncharacterised protein family UPF0102; KEGG: tbo:Thebr_1296 hypothetical protein; PFAM: Uncharacterised protein family UPF0102; Belongs to the UPF0102 family. (123 aa)    
Predicted Functional Partners:
rnhB
Ribonuclease HII/HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.851
AEM78827.1
KEGG: tbo:Thebr_1294 DNA protecting protein DprA; TIGRFAM: DNA recombination-mediator protein A; PFAM: DNA recombination-mediator protein A.
 
    0.841
AEM78832.1
Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein; PFAM: Magnesium chelatase, ChlI subunit; KEGG: thx:Thet_1194 Mg chelatase subunit ChlI; SMART: ATPase, AAA+ type, core.
 
  
 0.837
AEM78018.1
PFAM: Phosphoribosyltransferase; KEGG: tbo:Thebr_1833 phosphoribosyltransferase.
 
    0.712
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.637
ruvC
Crossover junction endodeoxyribonuclease ruvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
 
     0.556
codY
GTP-sensing pleiotropic transcriptional repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
       0.467
AEM78064.1
Universal protein YeaZ; KEGG: tbo:Thebr_1789 peptidase M22 glycoprotease; TIGRFAM: universal protein YeaZ; PFAM: Peptidase M22, glycoprotease.
 
     0.465
AEM79728.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; KEGG: bmd:BMD_0935 response regulator diguanylate cyclase/phosphodiesterase; SMART: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region.
   
    0.442
hslV
ATP-dependent protease hslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
       0.424
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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