| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEM78767.1 | AEM78884.1 | Thewi_1345 | Thewi_1462 | Cytidyltransferase-related domain protein; Manually curated; TIGRFAM: Cytidyltransferase-related; KEGG: tbo:Thebr_1234 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Belongs to the ribF family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.482 |
| AEM78767.1 | coaD | Thewi_1345 | Thewi_0621 | Cytidyltransferase-related domain protein; Manually curated; TIGRFAM: Cytidyltransferase-related; KEGG: tbo:Thebr_1234 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Belongs to the ribF family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.613 |
| AEM78767.1 | coaD-2 | Thewi_1345 | Thewi_1440 | Cytidyltransferase-related domain protein; Manually curated; TIGRFAM: Cytidyltransferase-related; KEGG: tbo:Thebr_1234 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Belongs to the ribF family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.617 |
| AEM78767.1 | nadE | Thewi_1345 | Thewi_0754 | Cytidyltransferase-related domain protein; Manually curated; TIGRFAM: Cytidyltransferase-related; KEGG: tbo:Thebr_1234 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Belongs to the ribF family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.505 |
| AEM78767.1 | ribBA | Thewi_1345 | Thewi_0023 | Cytidyltransferase-related domain protein; Manually curated; TIGRFAM: Cytidyltransferase-related; KEGG: tbo:Thebr_1234 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Belongs to the ribF family. | GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.696 |
| AEM78861.1 | AEM78863.1 | Thewi_1439 | Thewi_1441 | KEGG: tbo:Thebr_1328 hypothetical protein. | Methyltransferase; KEGG: tpd:Teth39_1301 putative methyltransferase; TIGRFAM: Conserved hypothetical protein CHP00095; PFAM: Protein of unknown function methylase putative. | 0.877 |
| AEM78861.1 | coaD-2 | Thewi_1439 | Thewi_1440 | KEGG: tbo:Thebr_1328 hypothetical protein. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.764 |
| AEM78863.1 | AEM78861.1 | Thewi_1441 | Thewi_1439 | Methyltransferase; KEGG: tpd:Teth39_1301 putative methyltransferase; TIGRFAM: Conserved hypothetical protein CHP00095; PFAM: Protein of unknown function methylase putative. | KEGG: tbo:Thebr_1328 hypothetical protein. | 0.877 |
| AEM78863.1 | coaD | Thewi_1441 | Thewi_0621 | Methyltransferase; KEGG: tpd:Teth39_1301 putative methyltransferase; TIGRFAM: Conserved hypothetical protein CHP00095; PFAM: Protein of unknown function methylase putative. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.699 |
| AEM78863.1 | coaD-2 | Thewi_1441 | Thewi_1440 | Methyltransferase; KEGG: tpd:Teth39_1301 putative methyltransferase; TIGRFAM: Conserved hypothetical protein CHP00095; PFAM: Protein of unknown function methylase putative. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.926 |
| AEM78884.1 | AEM78767.1 | Thewi_1462 | Thewi_1345 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Cytidyltransferase-related domain protein; Manually curated; TIGRFAM: Cytidyltransferase-related; KEGG: tbo:Thebr_1234 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Belongs to the ribF family. | 0.482 |
| AEM78884.1 | coaD | Thewi_1462 | Thewi_0621 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.932 |
| AEM78884.1 | coaD-2 | Thewi_1462 | Thewi_1440 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.933 |
| AEM78884.1 | coaE | Thewi_1462 | Thewi_0962 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.498 |
| AEM78884.1 | coaX | Thewi_1462 | Thewi_2322 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.942 |
| AEM78884.1 | ribBA | Thewi_1462 | Thewi_0023 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.661 |
| coaD | AEM78767.1 | Thewi_0621 | Thewi_1345 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Cytidyltransferase-related domain protein; Manually curated; TIGRFAM: Cytidyltransferase-related; KEGG: tbo:Thebr_1234 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Belongs to the ribF family. | 0.613 |
| coaD | AEM78863.1 | Thewi_0621 | Thewi_1441 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Methyltransferase; KEGG: tpd:Teth39_1301 putative methyltransferase; TIGRFAM: Conserved hypothetical protein CHP00095; PFAM: Protein of unknown function methylase putative. | 0.699 |
| coaD | AEM78884.1 | Thewi_0621 | Thewi_1462 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.932 |
| coaD | coaD-2 | Thewi_0621 | Thewi_1440 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.901 |
