STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM78898.1Asp/Glu/hydantoin racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (216 aa)    
Predicted Functional Partners:
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
    
 0.916
purQ
Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
     
  0.900
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
     
  0.900
AEM78897.1
KEGG: tmt:Tmath_1377 lipoprotein, YaeC family; TIGRFAM: Lipoprotein YaeC; PFAM: NLPA lipoprotein; Belongs to the nlpA lipoprotein family.
     
 0.739
metN
ABC transporter related protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
       0.649
AEM78896.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport systems inner membrane component; KEGG: tit:Thit_1328 binding-protein-dependent transport systems inner membrane component.
       0.649
AEM77590.1
Hypothetical protein; Manually curated; KEGG: tbo:Thebr_2222 D-alanine--D-alanine ligase.
 
  
 0.546
AEM79031.1
PFAM: ATP-NAD/AcoX kinase; KEGG: tbo:Thebr_0814 ATP-NAD/AcoX kinase.
  
     0.500
AEM78038.1
PFAM: Flagellar protein FlaG protein; KEGG: tbo:Thebr_1817 flagellar protein FlaG protein.
    
   0.445
AEM80023.1
KEGG: tbo:Thebr_2324 cyanophycin synthetase; TIGRFAM: Cyanophycin synthetase; PFAM: Mur ligase, central; Carbamoyl phosphate synthetase, large subunit, ATP-binding; ATP-grasp fold, RimK-type; Mur ligase, C-terminal; Belongs to the MurCDEF family.
  
  
 0.441
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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