STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM78919.1PFAM: Nitroreductase-like; KEGG: thx:Thet_1090 nitroreductase. (206 aa)    
Predicted Functional Partners:
AEM78918.1
PFAM: Protein of unknown function DUF81; KEGG: tbo:Thebr_0937 hypothetical protein.
  
  
 0.787
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.717
AEM79313.1
PFAM: AMP-dependent synthetase/ligase; KEGG: thx:Thet_1852 AMP-dependent synthetase and ligase.
   
 
 0.677
AEM79872.1
PFAM: ABC-2 type transporter; KEGG: tbo:Thebr_0201 ABC-2 type transporter.
  
  
 0.659
AEM78614.1
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: tbo:Thebr_1074 glyoxalase/bleomycin resistance protein/dioxygenase.
  
  
 0.535
ribBA
GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.524
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
       0.504
AEM78970.1
PFAM: ABC-2 type transporter; KEGG: ttm:Tthe_1165 ABC-2 type transporter.
  
  
 0.465
AEM79270.1
PFAM: ABC-2 type transporter; KEGG: cac:CA_C3268 hypothetical protein.
  
  
 0.465
AEM78920.1
KEGG: thx:Thet_1089 RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: RNA polymerase sigma factor 70, region 4 type 2; RNA polymerase sigma-70 region 2.
     
 0.462
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.