Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM78919.1PFAM: Nitroreductase-like; KEGG: thx:Thet_1090 nitroreductase. (206 aa)    
Predicted Functional Partners:
AEM78918.1
PFAM: Protein of unknown function DUF81; KEGG: tbo:Thebr_0937 hypothetical protein.
     
 0.781
AEM79872.1
PFAM: ABC-2 type transporter; KEGG: tbo:Thebr_0201 ABC-2 type transporter.
  
  
 0.768
AEM79313.1
PFAM: AMP-dependent synthetase/ligase; KEGG: thx:Thet_1852 AMP-dependent synthetase and ligase.
   
 
 0.713
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.606
AEM78614.1
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: tbo:Thebr_1074 glyoxalase/bleomycin resistance protein/dioxygenase.
  
  
 0.524
AEM78970.1
PFAM: ABC-2 type transporter; KEGG: ttm:Tthe_1165 ABC-2 type transporter.
  
  
 0.510
AEM79270.1
PFAM: ABC-2 type transporter; KEGG: cac:CA_C3268 hypothetical protein.
  
  
 0.510
AEM79158.1
PFAM: Homocysteine S-methyltransferase; Dihydropteroate synthase, DHPS; Methionine synthase, cobalamin (vitamin B12)-binding module, cap; Cobalamin (vitamin B12)-binding; KEGG: tbo:Thebr_0717 homocysteine S-methyltransferase.
  
  
 0.508
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
       0.505
tadA
Zinc-binding CMP/dCMP deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
  
 0.502
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.