STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM78941.1PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; KEGG: tbo:Thebr_0909 Cys/Met metabolism pyridoxal-phosphate-dependent protein. (396 aa)    
Predicted Functional Partners:
AEM79158.1
PFAM: Homocysteine S-methyltransferase; Dihydropteroate synthase, DHPS; Methionine synthase, cobalamin (vitamin B12)-binding module, cap; Cobalamin (vitamin B12)-binding; KEGG: tbo:Thebr_0717 homocysteine S-methyltransferase.
  
 
 0.978
AEM79159.1
PFAM: Methylenetetrahydrofolate reductase; KEGG: thx:Thet_1699 methylenetetrahydrofolate reductase.
  
 0.970
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
 0.935
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
 
 0.932
AEM78573.1
KEGG: tbo:Thebr_1034 cysteine synthase A; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.919
AEM79207.1
KEGG: tit:Thit_2087 cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.919
AEM78927.1
PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; KEGG: tmt:Tmath_1414 Cys/Met metabolism pyridoxal-phosphate-dependent protein.
  
  
 
0.908
AEM79550.1
KEGG: tbo:Thebr_0458 thioredoxin reductase; TIGRFAM: Thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
   
 
 0.908
AEM79071.1
KEGG: thx:Thet_0868 putative GAF sensor protein; PFAM: GAF; SMART: GAF.
     
 0.902
AEM78942.1
Purine or other phosphorylase family 1; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.
  
  
 0.777
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.