| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEM77537.1 | birA | Thewi_0021 | Thewi_1937 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.750 |
| AEM77537.1 | guaB | Thewi_0021 | Thewi_0666 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.771 |
| AEM77537.1 | ileS | Thewi_0021 | Thewi_1531 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.638 |
| AEM77537.1 | mtaD | Thewi_0021 | Thewi_1530 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 5-methylthioadenosine/S-adenosylhomocysteine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.443 |
| AEM77537.1 | mtnA | Thewi_0021 | Thewi_1528 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.440 |
| AEM78177.1 | mtaD | Thewi_0728 | Thewi_1530 | KEGG: thx:Thet_0626 hydroxymethylpyrimidine transporter CytX; TIGRFAM: Hydroxymethylpyrimidine transporter CytX; PFAM: Permease, cytosine/purines, uracil, thiamine, allantoin. | 5-methylthioadenosine/S-adenosylhomocysteine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.455 |
| AEM78941.1 | AEM78942.1 | Thewi_1526 | Thewi_1527 | PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; KEGG: tbo:Thebr_0909 Cys/Met metabolism pyridoxal-phosphate-dependent protein. | Purine or other phosphorylase family 1; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | 0.777 |
| AEM78941.1 | AEM78944.1 | Thewi_1526 | Thewi_1529 | PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; KEGG: tbo:Thebr_0909 Cys/Met metabolism pyridoxal-phosphate-dependent protein. | PFAM: Class II aldolase/adducin, N-terminal; KEGG: tbo:Thebr_0901 class II aldolase/adducin family protein. | 0.625 |
| AEM78941.1 | ileS | Thewi_1526 | Thewi_1531 | PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; KEGG: tbo:Thebr_0909 Cys/Met metabolism pyridoxal-phosphate-dependent protein. | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.414 |
| AEM78941.1 | mtaD | Thewi_1526 | Thewi_1530 | PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; KEGG: tbo:Thebr_0909 Cys/Met metabolism pyridoxal-phosphate-dependent protein. | 5-methylthioadenosine/S-adenosylhomocysteine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.443 |
| AEM78941.1 | mtnA | Thewi_1526 | Thewi_1528 | PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; KEGG: tbo:Thebr_0909 Cys/Met metabolism pyridoxal-phosphate-dependent protein. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.633 |
| AEM78942.1 | AEM78941.1 | Thewi_1527 | Thewi_1526 | Purine or other phosphorylase family 1; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; KEGG: tbo:Thebr_0909 Cys/Met metabolism pyridoxal-phosphate-dependent protein. | 0.777 |
| AEM78942.1 | AEM78944.1 | Thewi_1527 | Thewi_1529 | Purine or other phosphorylase family 1; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | PFAM: Class II aldolase/adducin, N-terminal; KEGG: tbo:Thebr_0901 class II aldolase/adducin family protein. | 0.741 |
| AEM78942.1 | guaB | Thewi_1527 | Thewi_0666 | Purine or other phosphorylase family 1; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.635 |
| AEM78942.1 | ileS | Thewi_1527 | Thewi_1531 | Purine or other phosphorylase family 1; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.512 |
| AEM78942.1 | mtaD | Thewi_1527 | Thewi_1530 | Purine or other phosphorylase family 1; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | 5-methylthioadenosine/S-adenosylhomocysteine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.987 |
| AEM78942.1 | mtnA | Thewi_1527 | Thewi_1528 | Purine or other phosphorylase family 1; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.992 |
| AEM78942.1 | speE | Thewi_1527 | Thewi_1288 | Purine or other phosphorylase family 1; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.937 |
| AEM78944.1 | AEM78941.1 | Thewi_1529 | Thewi_1526 | PFAM: Class II aldolase/adducin, N-terminal; KEGG: tbo:Thebr_0901 class II aldolase/adducin family protein. | PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; KEGG: tbo:Thebr_0909 Cys/Met metabolism pyridoxal-phosphate-dependent protein. | 0.625 |
| AEM78944.1 | AEM78942.1 | Thewi_1529 | Thewi_1527 | PFAM: Class II aldolase/adducin, N-terminal; KEGG: tbo:Thebr_0901 class II aldolase/adducin family protein. | Purine or other phosphorylase family 1; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | 0.741 |