STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM78962.1PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: tbo:Thebr_0865 2-hydroxyglutaryl-CoA dehydratase D-component. (427 aa)    
Predicted Functional Partners:
AEM78961.1
KEGG: tte:TTE1113 2-hydroxyglutaryl-CoA dehydratase activator; manually curated; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; ATPase, BadF/BadG/BcrA/BcrD type.
 
 0.985
AEM77838.1
KEGG: tmt:Tmath_0356 CoA-substrate-specific enzyme activase; TIGRFAM: CoA enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type.
 
 0.705
AEM79362.1
KEGG: tbo:Thebr_0566 CoA-substrate-specific enzyme activase; TIGRFAM: CoA enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type.
 
 0.702
AEM78960.1
KEGG: thx:Thet_1040 glycerate kinase; TIGRFAM: Glycerate kinase; PFAM: Glycerate kinase; Belongs to the glycerate kinase type-1 family.
       0.597
AEM78959.1
PFAM: Gluconate transporter; KEGG: tit:Thit_1448 gluconate transporter.
       0.557
bpsA
Protein of unknown function DUF43; Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.
  
     0.463
AEM78921.1
KEGG: tmt:Tmath_1408 hypothetical protein.
  
     0.459
AEM79787.1
PFAM: Septum formation initiator; KEGG: tbo:Thebr_0264 septum formation initiator.
  
     0.401
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.