STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM78977.1Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. (492 aa)    
Predicted Functional Partners:
AEM78655.1
KEGG: tbo:Thebr_1115 stage III sporulation protein AA; TIGRFAM: Sporulation stage III, protein AA; SMART: ATPase, AAA+ type, core.
  
  
 0.898
AEM77684.1
TIGRFAM: Sporulation stage III, transcriptional regulator SpoIIID; KEGG: tbo:Thebr_2141 sporulation transcriptional regulator SpoIIID.
  
  
 0.884
AEM78676.1
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.858
AEM78661.1
TIGRFAM: Sporulation stage III, protein AG; KEGG: thx:Thet_1372 stage III sporulation protein AG.
  
  
 0.856
AEM79883.1
KEGG: thx:Thet_2320 stage II sporulation protein R; TIGRFAM: Sporulation stage II, protein R; PFAM: Sporulation stage II, protein R.
  
   
 0.852
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.849
AEM77682.1
KEGG: tbo:Thebr_2143 stage II sporulation protein D; TIGRFAM: Sporulation stage II, protein D firmicutes; Sporulation stage II protein D, amidase enhancer LytB; PFAM: Sporulation stage II protein D, amidase enhancer LytB N-terminal.
  
  
 0.847
gpr
Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
   
 0.845
AEM78463.1
KEGG: tbo:Thebr_1436 stage II sporulation protein P; TIGRFAM: Sporulation stage II, protein P; PFAM: Sporulation stage II, protein P.
 
   
 0.845
AEM78658.1
KEGG: tbo:Thebr_1118 stage III sporulation protein AD; TIGRFAM: Sporulation stage III, protein AD; PFAM: Sporulation stage III, protein AD.
  
    0.839
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.