Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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AEM79000.1Hypothetical protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. (276 aa)    
Predicted Functional Partners:
AEM79686.1
TIGRFAM: Sporulation stage II, protein E; PFAM: Sporulation stage II, protein E C-terminal; KEGG: thx:Thet_2127 protein serine/threonine phosphatase; SMART: Protein phosphatase 2C-related.
  
  
 0.952
AEM78999.1
RNA polymerase, sigma 28 subunit, SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.951
AEM78998.1
RNA polymerase, sigma 28 subunit, SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.949
AEM79883.1
KEGG: thx:Thet_2320 stage II sporulation protein R; TIGRFAM: Sporulation stage II, protein R; PFAM: Sporulation stage II, protein R.
 
   
 0.882
AEM78997.1
KEGG: tbo:Thebr_0845 sporulation protein, YlmC/YmxH family; TIGRFAM: Sporulation protein YlmC/YmxH; PFAM: PRC-barrel.
 
     0.873
AEM78655.1
KEGG: tbo:Thebr_1115 stage III sporulation protein AA; TIGRFAM: Sporulation stage III, protein AA; SMART: ATPase, AAA+ type, core.
  
  
 0.858
AEM77684.1
TIGRFAM: Sporulation stage III, transcriptional regulator SpoIIID; KEGG: tbo:Thebr_2141 sporulation transcriptional regulator SpoIIID.
  
  
 0.855
AEM78481.1
KEGG: tbo:Thebr_1398 sporulation protein YqfD; TIGRFAM: Putative stage IV sporulation YqfD; PFAM: Putative stage IV sporulation YqfD.
  
   
 0.845
AEM79792.1
KEGG: tbo:Thebr_0259 sporulation protein YabP; TIGRFAM: Sporulation protein YabP; PFAM: Sporulation protein YabP.
  
  
 0.829
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.825
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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