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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (461 aa)    
Predicted Functional Partners:
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
 0.998
murE
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
 
0.995
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
  
 0.994
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
0.986
ddl
D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
 0.985
AEM79008.1
KEGG: tbo:Thebr_0834 stage V sporulation protein E; TIGRFAM: Stage V sporulation protein E; Cell division protein FtsW; PFAM: Cell cycle protein; Belongs to the SEDS family.
 
 
 0.964
AEM79436.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
   
 0.959
AEM77590.1
Hypothetical protein; Manually curated; KEGG: tbo:Thebr_2222 D-alanine--D-alanine ligase.
 
 
 0.948
AEM79013.1
SMART: PASTA; manually curated; TIGRFAM: Stage V sporulation protein D; KEGG: tbo:Thebr_0829 stage V sporulation protein D; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA.
 
  
 0.944
AEM80023.1
KEGG: tbo:Thebr_2324 cyanophycin synthetase; TIGRFAM: Cyanophycin synthetase; PFAM: Mur ligase, central; Carbamoyl phosphate synthetase, large subunit, ATP-binding; ATP-grasp fold, RimK-type; Mur ligase, C-terminal; Belongs to the MurCDEF family.
  
  
 0.894
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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