STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79025.1PFAM: Aminotransferase, class V/Cysteine desulfurase; KEGG: tbo:Thebr_0819 class V aminotransferase. (383 aa)    
Predicted Functional Partners:
thiI
tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 0.991
AEM77599.1
SirA-like domain-containing protein; PFAM: SirA-like; KEGG: tte:TTE0081 transcriptional regulator; Belongs to the sulfur carrier protein TusA family.
   
 0.970
AEM77868.1
PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; KEGG: tbo:Thebr_0875 UBA/ThiF-type NAD/FAD-binding protein.
   
 0.958
AEM79953.1
KEGG: tbo:Thebr_0126 SUF system FeS assembly protein; TIGRFAM: SUF system FeS cluster assembly, SufU scaffold; PFAM: NIF system FeS cluster assembly, NifU, N-terminal.
 
 0.942
AEM77911.1
KEGG: tbo:Thebr_1958 SUF system FeS assembly protein; TIGRFAM: SUF system FeS cluster assembly, SufU scaffold; PFAM: NIF system FeS cluster assembly, NifU, N-terminal.
 
 0.941
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
  
 
0.904
AEM78615.1
KEGG: tbo:Thebr_1075 Rrf2 family transcriptional regulator; TIGRFAM: Transcriptional regulator, Rrf2; PFAM: Transcriptional regulator, Rrf2.
 
  
 0.808
AEM79026.1
PFAM: Protein of unknown function DUF156; KEGG: tbo:Thebr_0818 hypothetical protein.
  
    0.740
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 
 0.734
AEM77601.1
SirA-like domain-containing protein; PFAM: SirA-like; KEGG: tte:TTE0083 transcriptional regulator; Belongs to the sulfur carrier protein TusA family.
   
 
 0.712
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.