STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79032.1Transketolase central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; KEGG: tbo:Thebr_0813 transketolase central region. (323 aa)    
Predicted Functional Partners:
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.999
AEM79705.1
PFAM: Dehydrogenase, E1 component; KEGG: tte:TTE0688 thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit.
 0.998
AEM79030.1
PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding; KEGG: thx:Thet_0907 catalytic domain-containing protein of components of various dehydrogenase complexes.
 0.997
AEM79707.1
Catalytic domain-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; E3 binding; Biotin/lipoyl attachment; KEGG: tte:TTE0690 dihydrolipoamide acyltransferase.
 
 0.990
AEM77797.1
KEGG: tmt:Tmath_0337 dihydrolipoamide dehydrogenase; TIGRFAM: Dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Biotin/lipoyl attachment; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
 
 0.907
AEM77606.1
KEGG: tmt:Tmath_0337 dihydrolipoamide dehydrogenase; TIGRFAM: Dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
 
 0.905
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.901
AEM79031.1
PFAM: ATP-NAD/AcoX kinase; KEGG: tbo:Thebr_0814 ATP-NAD/AcoX kinase.
 
  
 0.843
AEM79034.1
KEGG: tbo:Thebr_0811 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP02058; PFAM: Conserved hypothetical protein CHP02058.
 
     0.798
AEM77820.1
PFAM: NADH:flavin oxidoreductase/NADH oxidase, N-terminal; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cno:NT01CX_0026 2,4-dienoyl-CoA reductase, putative.
  
 0.722
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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