STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79058.1PFAM: Major facilitator superfamily MFS-1; KEGG: tbo:Thebr_0788 major facilitator superfamily protein. (418 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
    0.789
AEM79382.1
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
  
     0.641
AEM79038.1
KEGG: tbo:Thebr_0806 hypothetical protein.
  
     0.639
AEM77827.1
KEGG: thx:Thet_0286 aminopeptidase-like protein.
  
     0.624
AEM78011.1
PFAM: Spore germination protein-like Gmad2, bacteria; Lipoprotein LpqB, GerMN domain; KEGG: tmt:Tmath_0547 spore germination protein-like protein.
  
     0.561
AEM79405.1
KEGG: tmt:Tmath_1803 hypothetical protein.
  
     0.561
AEM78702.1
KEGG: tbo:Thebr_1160 hypothetical protein.
  
     0.544
AEM77679.1
KEGG: tte:TTE0165 hypothetical protein; PFAM: Cell surface receptor IPT/TIG; Fibronectin, type III; SMART: Fibronectin, type III; Cell surface receptor IPT/TIG.
  
     0.538
AEM79554.1
Thymidylate synthase complementing protein ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
 
     0.537
AEM78324.1
PFAM: Small acid-soluble spore protein, alpha/beta-type; KEGG: tbo:Thebr_1560 alpha/beta type small acid-soluble spore protein.
  
     0.534
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.