| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEM78273.1 | cobB | Thewi_0843 | Thewi_1667 | Hypothetical protein; Manually curated. | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.747 |
| AEM78476.1 | cobB | Thewi_1048 | Thewi_1667 | PFAM: Histidine triad (HIT) protein; KEGG: tbo:Thebr_1403 histidine triad (HIT) protein. | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.776 |
| AEM79068.1 | AEM79069.1 | Thewi_1668 | Thewi_1669 | KEGG: tbo:Thebr_0778 hypothetical protein. | KEGG: tit:Thit_1533 hypothetical protein. | 0.781 |
| AEM79068.1 | cobB | Thewi_1668 | Thewi_1667 | KEGG: tbo:Thebr_0778 hypothetical protein. | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.706 |
| AEM79069.1 | AEM79068.1 | Thewi_1669 | Thewi_1668 | KEGG: tit:Thit_1533 hypothetical protein. | KEGG: tbo:Thebr_0778 hypothetical protein. | 0.781 |
| AEM79069.1 | cobB | Thewi_1669 | Thewi_1667 | KEGG: tit:Thit_1533 hypothetical protein. | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.706 |
| AEM79367.1 | cobB | Thewi_1999 | Thewi_1667 | KEGG: thx:Thet_1886 hypothetical protein. | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.820 |
| cobB | AEM78273.1 | Thewi_1667 | Thewi_0843 | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | Hypothetical protein; Manually curated. | 0.747 |
| cobB | AEM78476.1 | Thewi_1667 | Thewi_1048 | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | PFAM: Histidine triad (HIT) protein; KEGG: tbo:Thebr_1403 histidine triad (HIT) protein. | 0.776 |
| cobB | AEM79068.1 | Thewi_1667 | Thewi_1668 | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | KEGG: tbo:Thebr_0778 hypothetical protein. | 0.706 |
| cobB | AEM79069.1 | Thewi_1667 | Thewi_1669 | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | KEGG: tit:Thit_1533 hypothetical protein. | 0.706 |
| cobB | AEM79367.1 | Thewi_1667 | Thewi_1999 | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | KEGG: thx:Thet_1886 hypothetical protein. | 0.820 |
| cobB | deoD | Thewi_1667 | Thewi_1678 | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | TIGRFAM: Purine nucleoside phosphorylase; HAMAP: Purine nucleoside phosphorylase deoD-type; KEGG: tbo:Thebr_0764 purine nucleoside phosphorylase; PFAM: Nucleoside phosphorylase. | 0.936 |
| cobB | nadD | Thewi_1667 | Thewi_1007 | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.925 |
| cobB | nadE | Thewi_1667 | Thewi_0754 | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.961 |
| cobB | nadK | Thewi_1667 | Thewi_1249 | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.918 |
| cobB | rpoC | Thewi_1667 | Thewi_2262 | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.677 |
| deoD | cobB | Thewi_1678 | Thewi_1667 | TIGRFAM: Purine nucleoside phosphorylase; HAMAP: Purine nucleoside phosphorylase deoD-type; KEGG: tbo:Thebr_0764 purine nucleoside phosphorylase; PFAM: Nucleoside phosphorylase. | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.936 |
| deoD | nadD | Thewi_1678 | Thewi_1007 | TIGRFAM: Purine nucleoside phosphorylase; HAMAP: Purine nucleoside phosphorylase deoD-type; KEGG: tbo:Thebr_0764 purine nucleoside phosphorylase; PFAM: Nucleoside phosphorylase. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.408 |
| nadD | cobB | Thewi_1007 | Thewi_1667 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.925 |
