Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
AEM79069.1KEGG: tit:Thit_1533 hypothetical protein. (493 aa)    
Predicted Functional Partners:
AEM79068.1
KEGG: tbo:Thebr_0778 hypothetical protein.
       0.781
cobB
NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
       0.706
AEM79070.1
Nitrogen-fixing NifU domain-containing protein; PFAM: NIF system FeS cluster assembly, NifU, C-terminal; KEGG: tbo:Thebr_0775 nitrogen-fixing NifU domain-containing protein.
       0.533
AEM79066.1
KEGG: tmt:Tmath_1536 cold-shock DNA-binding domain protein; PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein.
       0.516
AEM79071.1
KEGG: thx:Thet_0868 putative GAF sensor protein; PFAM: GAF; SMART: GAF.
       0.432
hslO
33 kDa chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
       0.408
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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