STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79069.1KEGG: tit:Thit_1533 hypothetical protein. (493 aa)    
Predicted Functional Partners:
AEM79068.1
KEGG: tbo:Thebr_0778 hypothetical protein.
       0.784
cobB
NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
       0.707
AEM79070.1
Nitrogen-fixing NifU domain-containing protein; PFAM: NIF system FeS cluster assembly, NifU, C-terminal; KEGG: tbo:Thebr_0775 nitrogen-fixing NifU domain-containing protein.
       0.535
AEM79066.1
KEGG: tmt:Tmath_1536 cold-shock DNA-binding domain protein; PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein.
       0.517
AEM79071.1
KEGG: thx:Thet_0868 putative GAF sensor protein; PFAM: GAF; SMART: GAF.
       0.432
hslO
33 kDa chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
       0.408
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.