STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
deoDTIGRFAM: Purine nucleoside phosphorylase; HAMAP: Purine nucleoside phosphorylase deoD-type; KEGG: tbo:Thebr_0764 purine nucleoside phosphorylase; PFAM: Nucleoside phosphorylase. (233 aa)    
Predicted Functional Partners:
AEM77984.1
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
  
 
 0.937
AEM77986.1
KEGG: tbo:Thebr_1873 pyrimidine-nucleoside phosphorylase; TIGRFAM: Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic; PFAM: Glycosyl transferase, family 3; Glycosyl transferase, family 3, N-terminal; Pyrimidine nucleoside phosphorylase, C-terminal.
  
 
 0.936
tdk
KEGG: tbo:Thebr_2159 thymidine kinase; HAMAP: Thymidine kinase, subgroup; PFAM: Thymidine kinase.
  
 
 0.922
cobB
NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
    
 0.920
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
 
 
 0.916
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.914
AEM79683.1
KEGG: tbo:Thebr_0309 hypoxanthine phosphoribosyltransferase; TIGRFAM: Hypoxanthine phosphoribosyl transferase; PFAM: Phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.913
AEM78393.1
PFAM: Quinolinate phosphoribosyl transferase; KEGG: tbo:Thebr_1506 quinolinate phosphoribosyl transferase; Belongs to the NAPRTase family.
     
 0.911
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
    
 0.910
AEM77883.1
KEGG: tbo:Thebr_1985 5'-nucleotidase domain-containing protein; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SH3, type 3; SMART: Bacterial SH3-like region.
  
 
 0.905
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.