STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79079.1KEGG: tbo:Thebr_0763 hypothetical protein; TIGRFAM: NGG1p interacting factor 3, NIF3; PFAM: NGG1p interacting factor 3, NIF3; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. (371 aa)    
Predicted Functional Partners:
AEM79080.1
PFAM: Protein of unknown function DUF633; KEGG: tbo:Thebr_0762 hypothetical protein.
 
  
 0.987
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
  
 0.730
AEM77922.1
KEGG: tbo:Thebr_1944 L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase, class I/II.
  
  
 0.722
hisC
TIGRFAM: Histidinol-phosphate aminotransferase; HAMAP: Histidinol-phosphate aminotransferase; KEGG: tit:Thit_1818 histidinol-phosphate aminotransferase; PFAM: Aminotransferase, class I/II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
 0.722
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
     
 0.652
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
     
 0.603
AEM78724.1
PFAM: Phosphoglycerate mutase; KEGG: tbo:Thebr_1192 phosphoglycerate mutase.
  
  
 0.588
AEM78648.1
KEGG: tbo:Thebr_1108 xylose isomerase domain-containing protein; PFAM: Xylose isomerase, TIM barrel domain; SMART: Endodeoxyribonuclease IV.
     
 0.574
pepT
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
  
    0.574
AEM79083.1
Deoxyguanosinetriphosphate triphosphohydrolase-like protein; SMART: Metal-dependent phosphohydrolase, HD region; TIGRFAM: Deoxyguanosinetriphosphate triphosphohydrolase; KEGG: tbo:Thebr_0759 deoxyguanosinetriphosphate triphosphohydrolase; HAMAP: Deoxyguanosinetriphosphate triphosphohydrolase-like protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; Belongs to the dGTPase family. Type 2 subfamily.
       0.518
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.