Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AEM79080.1PFAM: Protein of unknown function DUF633; KEGG: tbo:Thebr_0762 hypothetical protein. (234 aa)    
Predicted Functional Partners:
AEM79079.1
KEGG: tbo:Thebr_0763 hypothetical protein; TIGRFAM: NGG1p interacting factor 3, NIF3; PFAM: NGG1p interacting factor 3, NIF3; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
 
  
 0.990
AEM78620.1
PFAM: Protein of unknown function DUF965, bacterial; KEGG: tit:Thit_1042 protein of unknown function DUF965; Belongs to the UPF0297 family.
  
     0.733
AEM78892.1
PFAM: Fibronectin-binding A, N-terminal; Protein of unknown function DUF814; KEGG: tmt:Tmath_1373 fibronectin-binding A domain protein.
 
     0.634
AEM80020.1
PFAM: Protein of unknown function DUF951, bacterial; KEGG: tbo:Thebr_2321 hypothetical protein.
  
     0.602
whiA
Sporulation transcription regulator whiA; Involved in cell division and chromosome segregation.
  
     0.594
AEM78587.1
PFAM: Radical SAM; KEGG: tmt:Tmath_1071 radical SAM domain protein.
  
     0.557
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
       0.553
AEM78492.1
KEGG: tbo:Thebr_1388 CBS domain-containing protein.
 
     0.541
AEM78840.1
UPF0122 protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
     0.538
addA
ATP-dependent helicase/nuclease subunit A; ATP-dependent DNA helicase.
 
     0.534
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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