Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
AEM79091.1KEGG: tbo:Thebr_0751 RNA polymerase sigma-54 factor, RpoN; TIGRFAM: RNA polymerase sigma factor 54; PFAM: RNA polymerase sigma factor 54, DNA-binding; RNA polymerase sigma factor 54, core-binding; RNA polymerase sigma factor 54. (454 aa)    
Predicted Functional Partners:
AEM79373.1
Hypothetical protein; Manually curated; KEGG: tpd:Teth39_0540 phosphotransferase system, phosphocarrier protein HPr.
 
  
 0.902
AEM77696.1
KEGG: thx:Thet_0156 PTS system transcriptional activator; PFAM: RNA polymerase sigma factor 54, interaction; PRD; Phosphotransferase system, fructose subfamily IIA component; Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SMART: ATPase, AAA+ type, core.
 
 
 0.890
AEM77821.1
PAS sensor protein; SMART: PAS; manually curated; KEGG: dal:Dalk_1286 PAS modulated sigma54 specific transcriptional regulator, Fis family; TIGRFAM: PAS; PFAM: PAS fold.
 
   
 0.852
AEM77713.1
KEGG: thx:Thet_0167 PTS system transcriptional activator; PFAM: RNA polymerase sigma factor 54, interaction; PRD; Phosphotransferase system, fructose subfamily IIA component; SMART: ATPase, AAA+ type, core.
 
 
 
 0.835
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.832
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.831
AEM79476.1
PTS system transcriptional activator; KEGG: tbo:Thebr_1996 sigma-54 factor interaction domain-containing protein; PFAM: RNA polymerase sigma factor 54, interaction; PRD; Phosphotransferase system, fructose subfamily IIA component; SMART: ATPase, AAA+ type, core.
 
 
 
 0.826
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.822
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.817
AEM79294.1
KEGG: toc:Toce_1906 PTS system transcriptional activator; PFAM: RNA polymerase sigma factor 54, interaction; PRD; Phosphotransferase system, fructose subfamily IIA component; SMART: ATPase, AAA+ type, core.
 
 
 
 0.816
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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