Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM79102.1PFAM: Iron dependent repressor; KEGG: tbo:Thebr_0741 iron dependent repressor. (218 aa)    
Predicted Functional Partners:
recA
Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.917
recA-2
Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.917
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
 
 0.804
AEM78266.1
PFAM: Nucleotidyltransferase; KEGG: tbo:Thebr_1652 DNA polymerase beta domain-containing protein region.
  
     0.746
AEM79103.1
PFAM: Radical SAM; KEGG: tte:TTE1776 Fe-S oxidoreductase.
 
     0.732
AEM78702.1
KEGG: tbo:Thebr_1160 hypothetical protein.
  
     0.706
AEM79038.1
KEGG: tbo:Thebr_0806 hypothetical protein.
  
     0.630
AEM79654.1
PFAM: Protein of unknown function DUF1614; KEGG: tbo:Thebr_0335 hypothetical protein.
  
     0.628
AEM78674.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.592
AEM79711.1
Protein of unknown function DUF342; KEGG: tte:TTE1083 hypothetical protein; manually curated; PFAM: Protein of unknown function DUF342.
 
     0.592
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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