STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79105.1PFAM: Phosphoribulokinase/uridine kinase; KEGG: tbo:Thebr_0737 AAA ATPase. (547 aa)    
Predicted Functional Partners:
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 0.986
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.955
AEM77984.1
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
  
 0.951
pyrR
Bifunctional protein pyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
    
 0.944
AEM79089.1
KEGG: tbo:Thebr_0753 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain.
  
 
 0.942
cmk
TIGRFAM: Cytidylate kinase; HAMAP: Cytidylate kinase; KEGG: tbo:Thebr_1196 cytidylate kinase; PFAM: Cytidylate kinase region; Shikimate kinase.
 
 
 0.937
pyrF
TIGRFAM: Orotidine 5'-phosphate decarboxylase, subfamily 2, core; HAMAP: Orotidine 5'-phosphate decarboxylase; KEGG: tmt:Tmath_1385 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase, core; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 0.927
AEM77883.1
KEGG: tbo:Thebr_1985 5'-nucleotidase domain-containing protein; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SH3, type 3; SMART: Bacterial SH3-like region.
  
 
 0.922
AEM77986.1
KEGG: tbo:Thebr_1873 pyrimidine-nucleoside phosphorylase; TIGRFAM: Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic; PFAM: Glycosyl transferase, family 3; Glycosyl transferase, family 3, N-terminal; Pyrimidine nucleoside phosphorylase, C-terminal.
    
 0.921
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
  
 
 0.913
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.