STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79130.1HAD-superfamily hydrolase, subfamily IA, variant 1; KEGG: pmx:PERMA_1639 phosphoglycolate phosphatase (PGPase) (PGP); TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase. (215 aa)    
Predicted Functional Partners:
AEM77706.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; KEGG: thx:Thet_0160 phosphoglycerate dehydrogenase.
    
 0.905
AEM79298.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; KEGG: tte:TTE1946 glyoxylate reductase.
    
  0.903
AEM79131.1
KEGG: tit:Thit_1579 sugar-phosphate isomerase, RpiB/LacA/LacB family; TIGRFAM: Ribose/galactose isomerase; Ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase.
       0.750
AEM79132.1
Transketolase central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; KEGG: thx:Thet_1012 transketolase domain-containing protein.
       0.677
AEM79133.1
Transketolase domain-containing protein; PFAM: Transketolase, N-terminal; KEGG: thx:Thet_1011 transketolase.
       0.677
AEM79134.1
PFAM: Transaldolase; KEGG: tit:Thit_1582 transaldolase.
  
  
 0.623
AEM79129.1
KEGG: tit:Thit_1577 PHP domain protein; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal.
  
  
 0.607
AEM79128.1
KEGG: thx:Thet_1016 ketose-bisphosphate aldolase; TIGRFAM: Ketose-bisphosphate aldolase, class-II; PFAM: Ketose-bisphosphate aldolase, class-II.
  
  
 0.585
ribBA
GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.583
AEM77965.1
KEGG: tbo:Thebr_1890 pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
     
 0.551
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.