STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79150.1PFAM: Deoxyribonuclease/rho motif-related TRAM; Methyltransferase small; KEGG: tbo:Thebr_0722 TrmA family RNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (391 aa)    
Predicted Functional Partners:
AEM79412.1
KEGG: thx:Thet_1936 RNA methylase, NOL1/NOP2/sun family; TIGRFAM: Nop2p; PFAM: Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p.
 
  
 0.556
AEM79151.1
HutP family protein; PFAM: HutP; KEGG: dhd:Dhaf_1060 HutP family protein.
       0.512
AEM79177.1
KEGG: thx:Thet_1715 pyruvate kinase; TIGRFAM: Pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region.
 
   
 0.479
nnrD
YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]
 
    0.471
AEM79149.1
KEGG: tbo:Thebr_0723 hypothetical protein.
       0.464
AEM79977.1
KEGG: tbo:Thebr_0107 primosome, DnaD subunit; TIGRFAM: DnaD/phage-associated region; PFAM: DnaD/phage-associated region.
 
     0.446
AEM78781.1
PFAM: Phosphatidate cytidylyltransferase; KEGG: tbo:Thebr_1248 phosphatidate cytidylyltransferase; Belongs to the CDS family.
 
     0.441
pheT
TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; HAMAP: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; KEGG: tpd:Teth39_0772 phenylalanyl-tRNA synthetase subunit beta; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
    0.432
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
  
  
 0.411
AEM78003.1
tRNA methyltransferase complex GCD14 subunit; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
   
  
 0.408
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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