Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM79169.1ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport systems inner membrane component; KEGG: tmt:Tmath_1612 binding-protein-dependent transport systems inner membrane component. (212 aa)    
Predicted Functional Partners:
AEM79168.1
PFAM: ABC-type glycine betaine transport system, substrate-binding region; KEGG: tmt:Tmath_1611 substrate-binding region of ABC-type glycine betaine transport system.
 
 0.999
AEM79170.1
TIGRFAM: Glycine betaine/L-proline transport ATP-binding subunit; PFAM: ABC transporter-like; Cystathionine beta-synthase, core; KEGG: tmt:Tmath_1613 glycine betaine/L-proline ABC transporter, ATPase subunit; SMART: ATPase, AAA+ type, core; Cystathionine beta-synthase, core.
 
 0.999
AEM79171.1
KEGG: thx:Thet_1710 GntR family transcriptional regulator; PFAM: Regulator of K+ conductance, C-terminal; HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR.
 
     0.733
AEM79167.1
KEGG: thx:Thet_1706 2-isopropylmalate synthase/homocitrate synthase family protein; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase related; PFAM: Pyruvate carboxyltransferase; 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
    0.463
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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