STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79173.1Transcriptional regulator, Crp/Fnr family; KEGG: tbo:Thebr_0706 cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding; HTH transcriptional regulator, Crp; SMART: HTH transcriptional regulator, Crp. (228 aa)    
Predicted Functional Partners:
AEM79154.1
KEGG: thx:Thet_1694 hypothetical protein.
   
 
 0.746
AEM79174.1
KEGG: tbo:Thebr_0705 hypothetical protein.
 
     0.723
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.682
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.656
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.639
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.615
AEM79172.1
KEGG: tbo:Thebr_0707 MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein MatE; PFAM: Multi antimicrobial extrusion protein MatE.
       0.584
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.531
AEM77568.1
Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; HAMP linker domain; PAS fold; KEGG: tbo:Thebr_2247 PAS sensor protein; SMART: Metal-dependent phosphohydrolase, HD region; PAS; HAMP linker domain.
 
 
 0.522
AEM79378.1
KEGG: tbo:Thebr_0550 MIP family channel protein; TIGRFAM: Aquaporin; PFAM: Major intrinsic protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 0.513
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.