Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM79193.1Uncharacterized protein family UPF0052; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (324 aa)    
Predicted Functional Partners:
AEM79194.1
UPF0042 nucleotide-binding protein yhbJ; Displays ATPase and GTPase activities.
  
  
 0.978
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
       0.814
AEM79195.1
KEGG: tbo:Thebr_0683 PHP domain-containing protein; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal.
       0.788
whiA
Sporulation transcription regulator whiA; Involved in cell division and chromosome segregation.
  
  
 0.735
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
   0.543
AEM77537.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.482
AEM78438.1
KEGG: tmt:Tmath_0900 cell envelope-related transcriptional attenuator; TIGRFAM: Cell envelope-related transcriptional attenuator; PFAM: Cell envelope-related transcriptional attenuator.
  
     0.468
AEM79197.1
Hypothetical protein; Manually curated; KEGG: tit:Thit_1649 hypothetical protein.
       0.468
AEM79192.1
KEGG: thx:Thet_1730 alpha amylase catalytic region; PFAM: Glycosyl hydrolase, family 13, catalytic region; Alpha-amylase, C-terminal all beta; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; Alpha-amylase, C-terminal all beta.
       0.455
AEM77545.1
KEGG: tit:Thit_0029 cell envelope-related transcriptional attenuator; TIGRFAM: Cell envelope-related transcriptional attenuator; PFAM: Cell envelope-related transcriptional attenuator.
  
     0.429
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.