STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79204.1Copper-translocating P-type ATPase; KEGG: tte:TTE2463 cation transport ATPase; TIGRFAM: ATPase, P type, cation/copper-transporter; Copper ion-binding; ATPase, P-type, heavy metal translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; PFAM: ATPase, P-type, ATPase-associated region; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase. (796 aa)    
Predicted Functional Partners:
AEM79209.1
KEGG: tit:Thit_1657 copper ion binding protein; TIGRFAM: Copper ion-binding; PFAM: Heavy metal transport/detoxification protein.
 
 
0.948
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
     0.639
AEM79959.1
KEGG: tbo:Thebr_0120 glutaredoxin-like protein, YruB-family; TIGRFAM: Glutaredoxin-like protein, YruB; PFAM: Glutaredoxin.
  
 
 0.623
mnmA-2
tRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
       0.572
AEM77965.1
KEGG: tbo:Thebr_1890 pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
  
  
 0.554
AEM78605.1
PFAM: Protein of unknown function DUF156; KEGG: tbo:Thebr_1065 hypothetical protein.
 
  
 0.550
AEM77537.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.544
AEM77839.1
Cation diffusion facilitator family transporter; KEGG: tko:TK2009 cobalt/zinc/cadmium cation efflux pump protein; TIGRFAM: Cation efflux protein; PFAM: Cation efflux protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
 
  
 0.544
AEM77828.1
KEGG: thx:Thet_0287 regulatory protein ArsR; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR.
  
  
 0.535
AEM78968.1
KEGG: thx:Thet_0287 regulatory protein ArsR; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR.
  
  
 0.535
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.