STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79312.1PFAM: Protein of unknown function DUF624; KEGG: thx:Thet_1851 hypothetical protein. (199 aa)    
Predicted Functional Partners:
AEM79313.1
PFAM: AMP-dependent synthetase/ligase; KEGG: thx:Thet_1852 AMP-dependent synthetase and ligase.
       0.737
AEM79314.1
KEGG: thx:Thet_1853 glucokinase, ROK family; TIGRFAM: Glucokinase ROK; PFAM: ROK; ATPase, BadF/BadG/BcrA/BcrD type.
       0.722
AEM79315.1
HAMAP: hydrolase ycdX; PFAM: PHP, C-terminal; KEGG: tbo:Thebr_0592 PHP domain-containing protein; SMART: Polymerase/histidinol phosphatase, N-terminal.
       0.712
hprK
HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...]
       0.683
AEM79791.1
KEGG: tbo:Thebr_0260 hypothetical protein.
 
     0.669
AEM79251.1
KEGG: tmt:Tmath_1677 hypothetical protein.
  
     0.633
AEM77636.1
KEGG: tbo:Thebr_2179 hypothetical protein.
  
     0.601
AEM80009.1
KEGG: tte:TTE2353 ABC-type multidrug/protein/lipid transport system, ATPase component; PFAM: ABC transporter-like; ABC transporter, transmembrane region; SMART: ATPase, AAA+ type, core.
  
     0.587
AEM79806.1
PFAM: Uncharacterised conserved protein UCP028846; KEGG: thx:Thet_2249 hypothetical protein.
 
     0.583
AEM78090.1
PFAM: Lipase, class 2; KEGG: tte:TTE0555 acetyltransferase and hydrolase with the alpha/beta hydrolase fold.
  
     0.529
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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