Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM79320.1PFAM: Cell cycle protein; KEGG: tbo:Thebr_0587 cell cycle protein; Belongs to the SEDS family. (414 aa)    
Predicted Functional Partners:
AEM79319.1
PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: tbo:Thebr_0588 peptidoglycan glycosyltransferase.
 
 0.997
rodA
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
  
 
0.919
AEM79008.1
KEGG: tbo:Thebr_0834 stage V sporulation protein E; TIGRFAM: Stage V sporulation protein E; Cell division protein FtsW; PFAM: Cell cycle protein; Belongs to the SEDS family.
  
  
 
0.919
AEM78630.1
PFAM: Penicillin-binding protein, transpeptidase; KEGG: tbo:Thebr_1090 penicillin-binding protein transpeptidase.
 
 0.910
AEM79252.1
KEGG: tbo:Thebr_0641 peptidoglycan glycosyltransferase; manually curated; PFAM: Penicillin-binding protein, dimerisation domain.
 
 0.898
AEM79013.1
SMART: PASTA; manually curated; TIGRFAM: Stage V sporulation protein D; KEGG: tbo:Thebr_0829 stage V sporulation protein D; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA.
 
 0.884
AEM79005.1
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
 
 
 0.877
AEM79321.1
KEGG: tmt:Tmath_1750 FHA domain containing protein; PFAM: Forkhead-associated; SMART: Forkhead-associated.
 
   
 0.876
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.820
uvrC
UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
  
    0.799
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (16%) [HD]