Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AEM79325.1PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF; KEGG: tbo:Thebr_0582 PDZ/DHR/GLGF domain-containing protein. (414 aa)    
Predicted Functional Partners:
AEM79326.1
TIGRFAM: Peptidase S41A, C-terminal protease; PFAM: Peptidase S41; PDZ/DHR/GLGF; KEGG: tbo:Thebr_0581 carboxyl-terminal protease; SMART: Peptidase S41; PDZ/DHR/GLGF.
  
  
 0.852
comB
KEGG: tbo:Thebr_0583 2-phosphosulfolactate phosphatase; HAMAP: 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulpholactate phosphatase; Belongs to the ComB family.
       0.761
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
  
  
 0.729
AEM79328.1
Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
  
  
 0.707
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.702
AEM78926.1
KEGG: tbo:Thebr_0923 hypothetical protein.
  
     0.659
AEM79327.1
PFAM: Peptidase M23; KEGG: tbo:Thebr_0580 peptidase M23.
       0.648
AEM79826.1
PFAM: Copper amine oxidase-like, N-terminal; KEGG: slp:Slip_1153 copper amine oxidase domain protein.
  
 0.621
AEM79885.1
KEGG: tbo:Thebr_0187 spore germination protein; TIGRFAM: Spore germination GerAB; PFAM: Spore germination GerAB.
  
     0.599
AEM78072.1
Enoyl-CoA hydratase/isomerase; PFAM: Crotonase, core; KEGG: tte:TTE0544 3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
    
 0.596
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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