STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM79326.1TIGRFAM: Peptidase S41A, C-terminal protease; PFAM: Peptidase S41; PDZ/DHR/GLGF; KEGG: tbo:Thebr_0581 carboxyl-terminal protease; SMART: Peptidase S41; PDZ/DHR/GLGF. (398 aa)    
Predicted Functional Partners:
AEM79325.1
PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF; KEGG: tbo:Thebr_0582 PDZ/DHR/GLGF domain-containing protein.
     
 0.860
comB
KEGG: tbo:Thebr_0583 2-phosphosulfolactate phosphatase; HAMAP: 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulpholactate phosphatase; Belongs to the ComB family.
       0.762
AEM79327.1
PFAM: Peptidase M23; KEGG: tbo:Thebr_0580 peptidase M23.
 
    0.736
AEM79328.1
Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
     0.704
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
       0.662
AEM79330.1
Transcriptional regulator, CdaR; KEGG: tbo:Thebr_0577 helix-turn-helix fis-type.
       0.650
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]
     
 0.553
uvrA
UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
     
 0.547
AEM78779.1
TIGRFAM: Peptidase M50, putative membrane-associated zinc metallopeptidase; PFAM: Peptidase M50; PDZ/DHR/GLGF; KEGG: tbo:Thebr_1246 membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF.
 
  
 0.537
AEM77963.1
Hypothetical protein; Manually curated.
  
   0.515
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.