Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AEM79330.1Transcriptional regulator, CdaR; KEGG: tbo:Thebr_0577 helix-turn-helix fis-type. (350 aa)    
Predicted Functional Partners:
AEM79328.1
Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
       0.827
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
       0.827
AEM79327.1
PFAM: Peptidase M23; KEGG: tbo:Thebr_0580 peptidase M23.
       0.826
AEM79326.1
TIGRFAM: Peptidase S41A, C-terminal protease; PFAM: Peptidase S41; PDZ/DHR/GLGF; KEGG: tbo:Thebr_0581 carboxyl-terminal protease; SMART: Peptidase S41; PDZ/DHR/GLGF.
       0.649
comB
KEGG: tbo:Thebr_0583 2-phosphosulfolactate phosphatase; HAMAP: 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulpholactate phosphatase; Belongs to the ComB family.
       0.638
AEM77636.1
KEGG: tbo:Thebr_2179 hypothetical protein.
  
     0.602
AEM79325.1
PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF; KEGG: tbo:Thebr_0582 PDZ/DHR/GLGF domain-containing protein.
       0.573
AEM79359.1
KEGG: tbo:Thebr_0569 hypothetical protein.
  
     0.480
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.440
AEM79251.1
KEGG: tmt:Tmath_1677 hypothetical protein.
  
     0.416
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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