Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM79346.1PFAM: Sporulation stage II, protein E C-terminal; KEGG: tte:TTE0698 hypothetical protein. (392 aa)    
Predicted Functional Partners:
AEM79347.1
Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: Iron hydrogenase, large subunit, C-terminal; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Putative Fe-S cluster; PAS fold; KEGG: tte:TTE0697 ferredoxin 2; SMART: PAS.
 
     0.951
AEM79842.1
KEGG: tit:Thit_2175 putative PAS/PAC sensor protein; manually curated; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup.
 
     0.795
AEM79843.1
KEGG: elm:ELI_1213 NADH dehydrogenase subunit E.
 
    0.795
AEM77688.1
PFAM: Flagellar protein FlgJ, N-terminal; KEGG: tbo:Thebr_2137 flagellar protein FlgJ-like protein.
   
    0.743
AEM78136.1
KEGG: tbo:Thebr_1743 biotin and thiamin synthesis associated; PFAM: Biotin/thiamin synthesis-associated protein; Radical SAM; SMART: Elongator protein 3/MiaB/NifB.
  
    0.726
AEM78401.1
PFAM: ATP-binding region, ATPase-like; KEGG: thx:Thet_0789 putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
 
 0.697
AEM79734.1
PFAM: Sulphate transporter/antisigma-factor antagonist STAS; KEGG: tte:TTE1048 STAS domain-containing protein.
  
 
 0.603
AEM79735.1
PFAM: Sulphate transporter/antisigma-factor antagonist STAS; KEGG: tte:TTE1047 STAS domain-containing protein.
  
 
 0.603
AEM78807.1
KEGG: tbo:Thebr_1274 flagellar motor switch protein FliM; TIGRFAM: Flagellar motor switch protein FliM; PFAM: Flagellar motor switch protein FliM; Surface presentation of antigen (SpoA).
  
    0.585
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 
 0.553
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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